Table 8.
Effects of ANA-12 in female mice naïve to defeat on behavior during the social interaction test.
| Social interaction test | Hits DMSO | Hits ANA-12 | Misses DMSO | Misses ANA-12 |
|---|---|---|---|---|
| ACCLIMATION AND INTERACTION | ||||
| Time in interaction zone (empty) | 96.8 ± 15.1 | 97.0 ± 20.9 | 97.8 ± 21.2 | 104.2 ± 22.7 |
| Time in interaction zone (target) | 91.7 ± 12.0 | 85.9 ± 17.8 | 117.8 ± 12.5 | 95.1 ± 11.4 |
| Time in corners zone (empty) | 7.3 ± 2.7 | 10.5 ± 5.1 | 9.6 ± 4.5 | 10.3 ± 5.4 |
| Time in corners zone (target) | 8.7 ± 3.0 | 14.1 ± 5.0 | 4.4 ± 1.5 | 9.8 ± 3.9 |
| OPEN FIELD | ||||
| Time in center zone | 28.9 ± 2.5 | 32.3 ± 11.0 | 35.5 ± 11.7 | 23.4 ± 6.3 |
| Total distance | 23.3 ± 0.9 | 27.3 ± 3.0 | 23.8 ± 5.8 | 25.1 ± 2.9 |
All times in sec, all distances in m.
Data are shown as mean ± SE.
n = 5 per group.