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. Author manuscript; available in PMC: 2014 Jan 9.
Published in final edited form as: Pediatr Crit Care Med. 2013 Jun;14(5):10.1097/PCC.0b013e31828a742c. doi: 10.1097/PCC.0b013e31828a742c

Table 3. Postoperative Outcomes and Hematologic Data.

Patients Low-Dose Fentanyl Plus Placebo Low-Dose Fentanyl Plus Dexmedetomidine High-Dose Fentanyl Plus Placebo p
Length of CTICU stay (d) 1 (1–4) 2 (1–5) 1 (1–8) 0.5995
Length of hospital stay (d) 5 (3–15) 5 (3–23) 5.5 (3–32) 0.5561
Time on ventilator (hr) 3.79 (0–16) 2.4 (0–2.4) 10.75 (0–27.32) 0.43
Inotropic score on CTICU admission 2.5 (0–2.5) 2.5 (0–5) 2.5 (0–5) 0.2541
Inotropic score on postoperative day 1 2.5 (0–2.5) 2.5 (0–7.5) 2.5 (0–5) 0.1728
Bloodless throughout hospitalization (n, %) 0 (0) 0 (0) 4 (23.5) 0.0286
Preoperative platelet count (K/cu mm) 345 (216–511) 357 (187–521) 326 (201–696) 0.9681
Postoperative platelet count (K/cu mm) 106 (48–250) 116 (48–250) 132 (75–287) 0.5500
Postoperative prothrombin time (s) 20 (17.5–24.7) 19.2 (15.9–24.7) 18.8 (15.9–21.5)* 0.0466
Postoperative partial thromboplastin time (s) 42.5 (32–86) 44 (30–250) 40 (28–61) 0.3365
Postoperative international normalized ratio 1.7 (1.5–2.3) 1.6 (1.3–2.3) 1.6 (1.3–1.9)* 0.1018
Postoperative fibrinogen (mg/dL) 118 (68–165) 135 (68–222) 143 (93–222)# 0.1882
Postoperative absolute neutrophil count (cells/cu mm) 7,260 (3,100–16,184) 8,643 (4,514–13,272) 9,380 (3,690–16,960)# 0.1343

CTICU = cardiothoracic ICU.

*

p ≤ 0.03 versus low-dose fentanyl plus placebo.

#

p = 0.07 versus low-dose fentanyl plus placebo.

Data represent median (range) unless otherwise specified.