Table 1.
Clinical features of the recipients of liver grafts with an actuarial graft-to-recipient weight ratio < 0.8% and those with an actuarial graft-to-recipient weight ratio ≥ 0.8% n (%)
| Variable | Total (n = 196) | Group A (n = 45) | Group B (n = 151) | P value |
| Recipient factors | ||||
| Age (yr) | 42.60 ± 9.05 | 42.60 ± 8.90 | 42.60 ± 9.13 | 0.673 |
| Sex (male/female) | 171/25 | 40/5 | 131/20 | 0.706 |
| MELD score | 16.42 ± 9.86 | 13.87 ± 9.09 | 17.19 ± 9.97 | 0.012a |
| Child-Pugh score | 7.71 ± 2.12 | 7.27 ± 2.08 | 7.85 ± 2.20 | 0.118 |
| aGRWR (%) | 0.93 ± 0.18 | 0.71 ± 0.07 | 0.99 ± 0.15 | < 0.001a |
| ABO-compatibility (yes/no) | 161/35 | 36/9 | 125/26 | 0.669 |
| Median follow-up (mo) | 54.3 | 48.8 | 57.8 | 0.033a |
| 2001-2005/2006-2010 | 22/174 | 2/43 | 20/131 | 0.101 |
| ICU stay (h) | 307.32 ± 305.86 | 277.07 ± 270.91 | 316.34 ± 315.81 | 0.189 |
| Hospitalization time (d) | 39.45 ± 25.21 | 38.84 ± 22.49 | 39.64 ± 26.03 | 0.970 |
| Pre-transplant complications | ||||
| Encephalopathy | 21 (10.71) | 4 (8.89) | 17 (11.26) | 0.860 |
| GI bleeding | 12 (6.12) | 4 (8.89) | 8 (5.30) | 0.598 |
| Peritonitis | 8 (4.08) | 0 | 8 (5.30) | 0.251 |
| Uncontrolled ascites | 37 (18.88) | 7 (15.56) | 30 (19.87) | 0.516 |
| Renal insufficiency | 7 (3.57) | 0 | 7 (4.64) | 0.311 |
| Etiology | < 0.001a | |||
| Hepatic malignancy | 89 (45.41) | 28 (62.22) | 61 (40.40) | 0.010 |
| Viral cirrhosis | 66 (33.67) | 7 (15.56) | 59 (39.07) | 0.003 |
| Non-viral cirrhosis | 11 (5.61) | 4 (8.89) | 7 (4.64) | 0.472 |
| Cholestasis | 12 (6.12) | 1 (2.22) | 11 (7.28) | 0.374 |
| Acute liver failure | 11 (5.61) | 4 (8.89) | 8 (5.30) | 0.598 |
| Other | 6 (3.06) | 1 (2.22) | 5 (3.31) | 0.710 |
| Donor factors | ||||
| Age (yr) | 34.97 ± 10.20 | 34.29 ± 9.97 | 35.18 ± 10.30 | 0.727 |
| Sex (male/female) | 121/75 | 32/13 | 89/62 | 0.140 |
| Body mass index | 23.00 ± 2.55 | 22.96 ± 3.15 | 23.01 ± 2.36 | 0.654 |
| Relationship (blood-related/non-blood-related) | 20.41%/79.59% | 13.33%/86.67% | 22.52%/77.48% | 0.180 |
| 40/156 | 6/39 | 34/117 | ||
| Operative factors | ||||
| Operative time (min) | 659.02 ± 132.78 | 662.24 ± 113.65 | 658.05 ± 138.30 | 0.472 |
| Blood loss (mL) | 2183.93 ± 2022.02 | 2014.44 ± 1765.92 | 2234.44 ± 2095.04 | 0.444 |
| Ahepatic duration (min) | 93.36 ± 41.82 | 87.47 ± 30.94 | 95.11 ± 44.49 | 0.412 |
| MHV tributary drainage1 | 124 (63.27) | 31 (68.89) | 93 (61.69) | 0.373 |
| Concurrent splenectomy | 11 (5.61) | 3 (6.67) | 8 (5.30) | 0.726 |
| Types of biliary reconstruction2 | 180/16 | 44/1 | 136/15 | 0.178 |
| Complications after LDLT | ||||
| Postoperative bleeding | 8 (4.08) | 1 (2.22) | 7 (4.64) | 0.773 |
| Acute rejection | 9 (4.59) | 2 (4.44) | 7 (4.64) | 0.957 |
| Vascular complications | 7 (3.57) | 1 (2.22) | 6 (3.97) | 0.922 |
| Biliary complications | 21 (10.71) | 5 (11.11) | 16 (10.60) | 0.922 |
| SFSS | 16 (8.16) | 7 (15.56) | 9 (5.96) | 0.080 |
1
MHV tributary drainage includes MHV tributary reconstruction and MHV trunk inclusion;
2
Types of biliary reconstruction type includes duct-to-duct anastomosis and Roux-en-Y hepaticojejunostomy. GI: Gastrointestinal; MELD: Model for End-Stage Liver Disease; aGRWR: Actuarial graft-to-recipient weight ratio; MHV: Middle hepatic vein; LDLT: Living donor liver transplantation; SFSS: Small-for-size syndrome.
a
P < 0.05.