Table 2.

Differentially expressed microRNAs that were consistently reported in HNSCC (by at least 4 independent studies) (adopted from Chen et al., Oral Oncol. 2012;48(8):686-91)

MicroRNA	Chromosomal location	Mature miR sequence	Up-/down- regulation	References	No. of reports	Sample size (SCC/ctrl)
miR-21	17q23.1	uagcuuaucagacugauguuga	Up	[25-35]	11	192/112
miR-155	21q21.3	uuaaugcuaaucgugauaggggu	Up	[26,28,30,32,34,35]	6	133/68
miR-130b	22	cagugcaaugaugaaagggcau	Up	[28,30,33,34]	4	129/58
miR-223	Xq12	ugucaguuugucaaauacccca	Up	[28,30,34,35]	4	125/60
miR-31	9p21.3	aggcaagaugcuggcauagcu	Up	[25,26,28,34]	4	73/63
miR-7	9q21.32 or 15q26.1 or 19p13.3	uggaagacuagugauuuuguugu	Up	[29,35,102,103]	4	48/30
miR-34b	11q23.1	caaucacuaacuccacugccau	Up	[26,28,35,103]	4	31/26
miR-100	11q24.1	aacccguagauccgaacuugug	Down	[26,28-30,34]	5	127/67
miR-99a	21q21.1	aacccguagauccgaucuugug	Down	[26,28-30,34]	5	127/67
miR-375	2q35	uuuguucguucggcucgcguga	Down	[29,30,33,34]	4	129/58
miR-125b	11q24.1 or 21q21.1	ucccugagacccuaacuuguga	Down	[26,29,30,34]	4	117/57