Figure 2.

Anesthesia does not cause significant disturbances in the vital signs of pregnant guinea pigs. Close monitoring of vital signs was performed continuously and recorded every 15 minutes during exposure to anesthesia. No significant differences in any of the measured parameters in the experimental animals [exposed to isoflurane (0.55‐vol%) + N₂O (75‐vol%) + midazolam (1 mg/kg, i.m.)––(I + N + M)] (n = 3 pregnant guinea pigs) compared with the sham animals (n = 3 pregnant guinea pigs). Physiological range for guinea pigs for each parameter is indicated by a dotted line.