Table.

Clinic Information of Human Subjects

	Control (n=12)	Mild CKD Without Hypertension (n=24)	Severe CKD With Hypertension (n=32)
Age, y	43.6±12.2	44.2±11.3	46.4±10.5
Sex, M/F	7/5	14/10	22/10
Proteinuria/hematuria	ND	20/16	32/24
SBP, mm Hg	102.3±10.6	108.7±7.69	159.2±20.1*
DBP, mm Hg	75.4±12.1	70.8±7.3	96.2±12.7*
HB, g/L	129.76±17.68	129.2±17.3	125.1±18.63
HCT, %	38.80±2.51	37.38±5.29	35.63±5.06
TP, g/L	61.20±3.05	59.03±13.42	58.43±10.79
ALB, g/L	37.67±3.46	36.89±8.94	35.29±10.89
GLO, g/L	24.53±2.47	23.75±4.09	23.14±3.06
TG, mmol/L	1.92±0.46	2.07±0.38	1.98±0.26
TC, mmol/L	5.10±1.70	5.74±1.72	5.41±1.89
HDL, mmol/L	2.13±0.41	2.07±0.75	1.93±0.53
LDL, mmol/L	3.16±0.47	3.57±1.15	4.13±1.94
BUN, mmol/L	5.06±1.10	5.72±2.73	9.09±1.54*
Bcr, μmol/L	68.31±14.22	71.37±22.23	109.12±24.89*
eGFR, mL/min	86.31±17.16	77.79±15.87	52.01±19.61*

ALB indicates plasma albumin; Bcr, blood creatinine; BUN, blood urea nitrogen; CKD, chronic kidney disease; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; F, female; GLO, plasma globulin; HB, hemoglobin; HCT, hematocrit; HDL, high-density lipoproteins; LDL, low-density lipoproteins; M, male; SBP, systolic blood pressure; TC, total plasma cholesterol; TG, total plasma triglyceride; TP, total plasma protein. Kidneys of controls with normal kidney function and blood pressure were collected after 3 hours of acute kidney rupture.

^*Compared with control, P<0.05.