Table 1.

Examples of ischemia and reperfusion injury

Affected organ	Example of clinical manifestation
Single-organ ischemia and reperfusion
Heart	Acute coronary syndrome
Kidney	Acute kidney injury
Intestine	Intestinal ischemia and reperfusion; multiorgan failure
Brain	Stroke
Multiple-organ ischemia and reperfusion
Trauma and resuscitation	Multiple organ failure; acute kidney injury; intestinal injury
Circulatory arrest	Hypoxic brain injury; multiple organ failure; acute kidney injury
Sickle cell disease	Acute chest syndrome; pulmonary hypertension, priapism, acute kidney injury
Sleep apnea	Hypertension; diabetes
Ischemia and reperfusion during major surgery
Cardiac surgery	Acute heart failure after cardiopulmonary bypass
Thoracic surgery	Acute lung injury
Peripheral vascular surgery	Compartment syndrome of extremity
Major vascular surgery	Acute kidney injury
Solid organ transplantation	Acute graft failure; early graft rejection