Fig. 4.
The distribution (amount in blood or tissue/amount injected; mean ± S.D.) of 20 mg/kg (A) 3H-Taxol and (B) 3H-PTX/FPI-749 nanocrystals. Inset: The comparison of % amount of 3H-Taxol and 3H-PTX/FPI-749 nanocrystals (mean ± S.D.) in tumor. In tumor, 3H-Taxol was significantly higher than that of 3H-PTX nanocrystals regardless the time point (p < 0.0001). The term “asap” refers to 5 and 11 minutes post-injection time of 3H-Taxol and 3H-PTX/FPI-749 nanocrystals, respectively.