TABLE 4.
Differences in peripartum morbidity between subjects with eclampsia compared to those without
| Rate per 100 of morbidity unless otherwise specified (no. of cases) |
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|---|---|---|---|---|---|---|
| Peripartum morbidity | Eclampsia present (n = 1888) | Eclampsia absent (n = 2,768,983) | Unadjusted OR (95% CI) | P value | Adjusted OR (95% CI) | P value |
| Fetal distress (per 1000) | 22.78 (43) | 5.93 (16,423) | 3.91 (2.89–5.29) | < .001 | 3.45 (2.54–4.68) | < .001 |
|
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| Failed induction | 4.71 (89) | 1.54 (42,545) | 3.17 (2.56–3.92) | < .001 | 2.94 (2.37–3.64) | < .001 |
|
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| Abnormal fetal heart rate | 19.28 (364) | 12.1 (335,427) | 1.73 (1.55–1.94) | < .001 | 1.67 (1.49–1.87) | < .001 |
|
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| Intrauterine fetal demise (per 1000) | 13.77 (26) | 3.90 (10,804) | 3.57 (2.42–5.25) | < .001 | 3.04 (2.06–4.49) | < .001 |
|
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| Uterine rupture (per 10,000) | 31.78 (6) | 5.3 (1477) | 5.97 (2.68–13.33) | .001 | 5.53 (2.47–12.39) | < .001 |
|
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| Cesarean delivery | 61.86 (1168) | 29.3 (811,453) | 3.91 (3.57–4.29) | < .001 | 4.01 (3.64–4.41) | < .001 |
|
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| Postpartum hemorrhage | 6.41 (121) | 2.6 (72,987) | 2.53 (2.10–3.04) | < .001 | 2.33 (1.94–2.80) | < .001 |
|
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| Venous thromboembolism (per 10,000) | 42.37 (8) | 1.77 (492) | 23.95 (11.89–48.22) | < .001 | 10.71 (5.14–22.32) | < .001 |
|
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| Amniotic fluid embolism (per 100,000) | 158.90 (3) | 4.69 (130) | 33.90 (10.78–106.57) | < .001 | 11.94 (3.63–39.21) | < .001 |
|
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| Cerebrovascular hemorrhage/disorders (per 10,000) | 195.97 (37) | 1.21 (335) | 165.20 (117.28–232.70) | < .001 | 112.15 (77.47–162.35) | < .001 |
|
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| Peripartum cardiomyopathy (per 10,000)a | 347.49 (9) | 6.54 (1307) | 55.04 (28.25–107.26) | < .001 | 12.88 (6.08–27.25) | < .001 |
|
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| Death (per 100,000) | 476.69 (9) | 7.87 (218) | 60.83 (31.19–118.67) | < .001 | 16.69 (8.06–34.57) | < .001 |
CI, confidence interval; OR, odds ratio.
a
Calculated for years 2003 through 2007 only (eclampsia present = 1319; eclampsia absent = 1,998,567). Not significant: dilation and curettage postdelivery, manual extraction of placenta, retained placenta, bladder repair, hematoma evacuation, cervical laceration repair, failed operative vaginal delivery, hysterectomy.