Figure 3.
Inhibition of PGE2 levels by CMC 2.5 in PBMC cells. PBMC cells (5 × 105 cells/well) were cultured in serum-free media (37°C, 95% air, 5% CO2) for 18 hours with LPS (P. gingivalis, 50 ng/mL) or vehicle alone. CMC 2.5 was added at final concentrations of 2 or 5 μM. Conditioned medium was analysed for PGE2 by ELISA. Each value represents the mean of 3 cultures ± S.E.M. *P < 0.05.