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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2013 Oct 23;20(1):10.1016/j.bbmt.2013.10.018. doi: 10.1016/j.bbmt.2013.10.018

Table 1.

Patient-, disease-, and transplantation-related characteristics

Characteristic of patients N (%)
Number of patients 233
Number of centers 83
Age, median(range), years 55 (19 – 79)
 18–40 12 (5)
 41–60 157 (67)
 >60 64 (27)
Gender
 Male 151 (65)
 Female 82 (35)
Karnofsky score
 <90% 84 (36)
 90–100% 135 (58)
 Missing 14 (6)
Time from diagnosis to transplant (range), months 15 (2 – 305)
Constitutional symptoms prior to HCT
 No 182 (78)
 Yes 42 (18)
 Missing 9 (4)
Circulating blasts in blood at HCT
 Absent 132 (57)
 ≥1% 101 (43)
Spleen status at transplant
 Spleen not palpable 52 (22)
 Splenomegaly 113 (48)
 Splenectomy 59 (25)
 Missing 9 (4)
Cytogenetics prior to HCT
 Not evaluable/missing 84(36)
 Normal Karyotype 89 (38)
 Abnormal 66 (28)
  Unfavorable 30(13)
  Other abnormalities 30 (13)
Hemoglobin at HCT
 <100g/L 148(64)
 ≥100g/L 85 (36)
Platelet count at transplant (range), × 109/L 121 (5 – 1835)
Platelet count prior to transplant
 <100 × 109/L 94 (40)
 ≥100 × 109/L 116 (50)
 Missing 23 (10)
WBC count at transplant (range), × 109/L 6 (<1 – 431)
DIPSS at transplant
 Low risk 27 (12)
 Int-1 114 (49)
 Int-2 86 (37)
 High-risk 3 (1)
 Missing 3 (1)
Graft type
 Bone marrow 28 (12)
 Peripheral blood 205 (88)
Donor type
 HLA-identical sibling 79 (34)
 Well-matched URD 104 (45)
 Partially matched URD 40 (17)
 Mismatched URD 10 (4)
D-R CMV status
 +/+ 72 (31)
 +/− 26 (11)
 −/+ 55 (24)
 −/− 60 (26)
 Missing 20 (9)
Conditioning regimen
 FluTBI-based 51 (22)
 FluMel-based 65 (28)
 FluBu-based 89 (38)
 Others 28 (12)
ATG or alemtuzumab use
 ATG 110 (47)
 Alemtuzumab 13 (6)
GVHD prophylaxis
 Tarcrolimus-based 105 (45)
 Cyclosporine-based 124 (53)
 Other GVHD prophylaxis 4 (2)
Year of transplant
 1997–2001 26 (11)
 2002–2006 116 (50)
 2007–2010 91 (39)
Median follow-up of survivors, range, months 50 (3 – 134)