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Photomicrographs of hippocampus showing immunoreactivity for phosphorylated neurofilament (SMI-31; A–C), for tau (D–F), and for paired helical filament (PHF; G–I) in rats carrying IL-1β pellets (A, D, G), sham (inert) pellets (B, E, H), and normal (unoperated) (C, F, I) rats. Phosphorylated neurofilament, Tau, and PHF protein immunoreactivity is increased in perikarya and processes of neurons in hippocampus of IL-1β pellet-implanted rats. Bars, 15 μm.
