Figure 2.
Activities of Krebs cycle enzymes of the mitochondrial fractions from control and CR mice. Four representative enzymes from the cycle were assayed as described in the text. A, citrate synthase; B, aconitase; C, succinate dehydrogenase (complex II); D, malate dehydrogenase. All enzyme activities were expressed as μmol/min/mg protein and presented as mean ± SEM (n = 6). Bars within a group, and between groups, that do not share the same letter are significantly different (P < 0.05). The symbol (~) is used to indicate a trend towards an increase or a decrease (P < 0.10) when the difference is not significant. Black bar, M1; Gray bar, M3; Light gray bar, M10.