Table 4.

Early body size and breast cancer risk among AA and EA postmenopausal women (excluding HRT users).

	AA (n=752)					EA (n=375)
	Cases/Controls	OR	95% CI	OR2	95% CI	Cases/Controls	OR	95% CI	OR	95% CI
Relative height at 7 or 8*a
Shortest/much shorter	43/26	1.84	1.06–3.17	1.95	1.12–3.42	20/22	0.82	0.38–1.80	0.76	0.34–1.69
Somewhat shorter	38/51	0.76	0.47–1.24	0.86	0.52–1.42	22/22	0.91	0.42–1.99	0.87	0.39–1.92
About the same	201/211	REF		REF		105/78	REF		REF
Somewhat taller	43/49	0.90	0.56–1.46	0.96	0.59–1.57	31/26	1.17	0.59–2.34	1.17	0.58–2.37
Tallest/much taller	47/41	1.38	0.85–2.26	1.34	0.81–2.21	24/24	1.00	0.48–2.08	1.03	0.48–2.19
Relative height at menarche*a
Shortest/much shorter	33/23	1.68	0.93–3.03	1.76	0.96–3.20	16/16	0.77	0.32–1.86	0.80	0.32–1.99
Somewhat shorter	45/45	1.05	0.65–1.70	1.12	0.68–1.84	27/29	1.19	0.59–2.40	1.12	0.55–2.28
About the same	202/214	REF		REF		105/78	REF		REF
Somewhat taller	46/58	0.87	0.55–1.38	0.89	0.55–1.42	28/25	0.75	0.37–1.53	0.70	0.34–1.44
Tallest/much taller	47/37	1.48	0.90–2.45	1.40	0.84–2.33	27/23	1.19	0.58–2.46	1.05	0.50–2.21
Relative height at 15 or 16*a
Shortest/much shorter	29/23	1.45	0.79–2.65	1.58	0.85–2.94	17/14	1.02	0.42–2.46	0.99	0.40–2.42
Somewhat shorter	48/53	1.05	0.66–1.66	1.12	0.70–1.79	37/41	0.90	0.47–1.72	0.94	0.49–1.81
About the same	219/228	REF		REF		105/76	REF		REF
Somewhat taller	38/43	1.01	0.61–1.67	1.00	0.60–1.69	25/29	0.61	0.30–1.24	0.61	0.29–1.26
Tallest/much taller	39/31	1.48	0.87–2.53	1.37	0.80–2.37	19/12	1.82	0.75–4.44	1.69	0.68–4.21
Relative weight at 7 or 8*a
Thinnest/much thinner	62/56	1.20	0.77–1.86	1.11	0.70–1.76	29/20	1.19	0.56–2.53	0.95	0.43–2.09
Somewhat thinner	84/70	1.27	0.85–1.89	1.23	0.81–1.86	46/30	1.07	0.56–2.05	0.86	0.44–1.69
About the same	174/183	REF		REF		90/80	REF		REF
Somewhat heavier	43/48	0.87	0.53–1.41	0.83	0.49–1.40	32/33	0.65	0.34–1.26	0.71	0.35–1.44
Heaviest/much heavier	7/21	0.34	0.13–0.85	0.31	0.11–0.88	5/9	0.36	0.10–1.29	0.62	0.15–2.49
Relative weight at menarche*a
Thinnest/much thinner	58/54	1.14	0.73–1.79	1.06	0.66–1.71	22/15	0.91	0.39–2.13	0.78	0.33–1.89
Somewhat thinner	76/67	1.19	0.79–1.80	1.13	0.74–1.72	48/30	1.00	0.52–1.93	0.85	0.43–1.67
About the same	186/181	REF		REF		93/70	REF		REF
Somewhat heavier	45/52	0.97	0.60–1.56	0.89	0.53–1.49	35/45	0.42	0.22–0.79	0.47	0.23–0.93
Heaviest/much heavier	6/24	0.23	0.09–0.60	0.23	0.08–0.63	5/11	1.18	0.05–0.62	0.18	0.04–0.79
Relative weight at 15 or 16*a
Thinnest/much thinner	50/46	1.18	0.73–1.89	1.11	0.67–1.83	17/14	0.92	0.37–2.30	0.75	0.29–1.93
Somewhat thinner	73/64	1.19	0.78–1.79	1.15	0.75–1.77	53/28	1.52	0.81–2.82	1.34	0.70–2.56
About the same	201/198	REF		REF		96/87	REF		REF
Somewhat heavier	41/50	0.94	0.58–1.53	0.87	0.51–1.48	30/36	0.59	0.31–1.16	0.74	0.35–1.54
Heaviest/much heavier	7/20	0.37	0.15–0.93	0.39	0.14–1.09	7/7	0.61	0.18–2.08	0.93	0.23–3.81
BMI at age 20 yrs.b
<25	279/286	REF		REF		183/148	REF		REF
25–29.9	46/51	0.99	0.63–1.56	1.25	0.76–2.06	12/10	0.86	0.32–2.27	1.32	0.47–3.71
≥30	14/23	0.68	0.33–1.38	1.05	0.47–2.35	3/11	0.06	0.01–0.40	0.12	0.02–0.82
p for trend			0.37		0.60			0.004		0.09
Weight gain since age 20, kgc
Q 1	55/68	REF		REF		41/32	REF		REF
Q 2	81/86	1.17	0.71–1.92	1.21	0.73–2.01	35/30	0.74	0.33–1.66	0.90	0.39–2.06
Q 3	83/90	1.20	0.73–1.96	1.29	0.75–2.21	51/40	0.69	0.33–1.45	0.94	0.42–2.13
Q 4	99/96	1.21	0.74–1.95	1.38	0.72–2.64	55/46	0.63	0.30–1.30	1.26	0.43–3.69
p for trend			0.52		0.37			0.25		0.59

^*compared to peers

OR1: Adjusted for age, ethnicity, country of origin, education, family history of breast cancer, history of benign breast disease, age at menarche, age at menopause, parity, breastfeeding status, age at first birth, oral contraceptive use.

OR2:

^afurther adjusted for BMI at age 20;

^bfurther adjusted for height and weight at menarche;

^cfurther adjusted for current BMI