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. 2013 Dec 19;2(6):e000410. doi: 10.1161/JAHA.113.000410

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© 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 5. — Global cardiac contractile dysfunction. Peak strain values in speckle‐tracking echocardiography had a linear correlation with cardiac dilatation (n=38; A) and reduced contractility (n=38; B) measured in M‐mode/2‐dimensional echocardiography. Peak strains significantly decreased following transverse aortic constriction (TAC) in ATP‐sensitive K⁺ channel knockout (Pre n=10, Post n=5; C and D). *P<0.05 vs Pre. 2 wk indicates 2 weeks; 3 m‐TAC, 3 months post‐TAC; CI, confidence interval; LV, left ventricular.