Table 7.
Reclassification by RHI Addition to FRS Alone and FRS, BNP and SYNTAXsc (n=528)
| Low‐Intermediate Risk | High Risk | Very High Risk | |
|---|---|---|---|
| Risk Category Using FRS Alone | New Risk Category Using FRS+RHI | ||
| Patients Without Cardiovascular Events | |||
| Low‐intermediate risk | 2 | 0 | 0 |
| High risk | 135 | 159 | 93 |
| Very high risk | 6 | 14 | 14 |
| Patients With Cardiovascular Events | |||
| Low‐intermediate risk | 0 | 0 | 0 |
| High risk | 9 | 34 | 48 |
| Very high risk | 0 | 3 | 11 |
| Risk Category Using FRS+BNP+SYNTAXsc | New Risk Category by FRS+BNP+SYNTAXsc+RHI | ||
|---|---|---|---|
| Patients Without Cardiovascular Events | |||
| Low‐intermediate risk | 136 | 27 | 1 |
| High risk | 63 | 78 | 22 |
| Very high risk | 15 | 16 | 65 |
| Patients With Cardiovascular Events | |||
| Low‐intermediate risk | 4 | 6 | 0 |
| High risk | 4 | 15 | 20 |
| Very high risk | 1 | 3 | 52 |
According to the Framingham Risk Score that was calculated for a 2‐year cardiovascular event risk, low‐intermediate risk was <12%, high risk was 12% to 25%, and very high risk was >25%. The overall net reclassification index was 48.9%, P<0.0001 when RHI was used in conjunction with FRS alone, and 27.5%, P<0.0001 when used in conjunction with FRS+BNP+SYNTAXsc. BNP indicates B‐type natriuretic peptide; FRS, Framingham Risk Score; RHI, reactive hyperemia‐peripheral arterial tonometry index; SYNTAXsc, Synergy Between PCI With Taxus and Cardiac Surgery score.