Table 3.
A Selective List of Hypoxia‐Inducible Genes Differentially Regulated in fatVHLko Adipose Tissue (n=3)
| Gene Symbol | Gene Name | NCBI Accession | FDR Adjusted P Value | Fold‐Change (KO vs WT) |
|---|---|---|---|---|
| Hmox1 | Heme oxygenase 1 | NM_010442 | 0.0064 | 5.54 |
| Thbs1 | Thrombospondin 1 | NM_011580 | 0.0039 | 4.86 |
| Serpine1 | Plasminogen activator inhibitor‐1 (PAI‐1) | NM_008871 | 0.0067 | 4.70 |
| Adm | Adrenomedullin | NM_009627 | 0.0059 | 3.80 |
| Aldh3b2 | Aldehyde dehydrogenase 3B2 | NM_001177438 | 0.0110 | 3.73 |
| Slc2a3 | Solute carrier family 2 (facilitated glucose transporter) member 3 or Glut3 | NM_011401 | 0.0069 | 3.26 |
| Lep | Leptin | NM_008493 | 0.0471 | 3.08 |
| Egln3 | EGL (egg‐laying abnormal) 9 homolog 3 (Caenorhabditis elegans) or PHD3 (prolyl hydroxylase domain‐containing 3) | NM_028133 | 0.0041 | 2.76 |
| Upp1 | Uridine phosphorylase 1 | NM_009477 | 0.0109 | 2.27 |
| Pgf | Placental growth factor | NM_008827 | 0.0380 | 2.03 |
FDR indicates false discovery rate; KO, knockout; NCBI, National Center for Biotechnology Information; WT, wild type.