Table 5.
Inflammatory/Immune Genes Differentially Regulated in fatVHLko Adipose Tissue (n=3)
| Gene Symbol | Gene Name | NCBI Accession | FDR Adjusted P Value | Fold‐Change (KO vs WT) |
|---|---|---|---|---|
| Igk‐V1 | Z95477 | 0.0019 | 20.42 | |
| Igk | BC128281 | 0.0052 | 11.92 | |
| Igk‐V28 | DQ078272 | 0.0042 | 8.88 | |
| Igkv4‐71 | NC_000072 | 0.0039 | 8.77 | |
| Igj | NM_152839 | 0.0056 | 7.29 | |
| Igh | BC092065 | 0.0236 | 7.19 | |
| Igk‐V19‐14 | U59155 | 0.0065 | 6.48 | |
| Igl‐V2 | NC_000082 | 0.0025 | 3.05 | |
| Ccl8 (MCP‐2) | Chemokine (C‐C motif) ligand 8 | NM_021443 | 0.0160 | 3.65 |
| Ccl7 (MCP‐3) | Chemokine (C‐C motif) ligand 7 | NM_013654 | 0.0177 | 2.73 |
| Ccl3 (MIP‐1a) | Chemokine (C‐C motif) ligand 3 | NM_011337 | 0.0309 | 2.46 |
| Ccl2 (MCP‐1) | Chemokine (C‐C motif) ligand 2 | NM_011333 | 0.0267 | 2.32 |
| Ccl24 (MPIF‐2) | Chemokine (C‐C motif) ligand 24 | NM_019577 | 0.0041 | 2.25 |
| Ccl6 (MRP‐1) | Chemokine (C‐C motif) ligand 6 | NM_009139 | 0.0115 | 2.01 |
| Cxcl9 (Mig) | Chemokine (C‐X‐C motif) ligand 9 | NM_008599 | 0.0285 | 2.00 |
| Ifi27l2a | Interferon α–inducible protein 27 like 2A | NM_029803 | 0.0255 | 2.54 |
| Vcam1 | Vascular cell adhesion molecule 1 | NM_011693 | 0.0086 | 2.30 |
| Cd53 | CD53 antigen | NM_007651 | 0.0076 | 2.25 |
| Cd93 (Ly68) | CD93 antigen | NM_010740 | 0.0083 | 2.10 |
| Ly86 (MD1) | Lymphocyte antigen 86 | NM_010745 | 0.0055 | 2.09 |
FDR indicates false discovery rate; KO, knockout; NCBI, National Center for Biotechnology Information; WT, wild type.