Table 3.
Cardiac Proteins Detected Differentially in the Very Early Phase of AMI
| UniProt Accession | Protein Name | Cellular Component | Area I vs Control | Area II vs Control | ||
|---|---|---|---|---|---|---|
| Fold‐Change | P Value | Fold‐Change | P Value | |||
| P05413_FABPH | Fatty acid–binding protein, heart (H‐FABP) | Cytoplasm | −2.0 | 0.016 | −1.4 | 0.310 |
| O94875_SRBS2 | Sorbin and SH3 domain‐containing protein 2 (SORBS2) | Cytoplasm | −1.2 | 0.690 | −12.8 | 0.016 |
| P54296_MYOM2 | Myomesin‐2 | Cytoplasm | −1.1 | 0.690 | −1.7 | 0.016 |
| Q9UKX3_MYH13 | Myosin heavy‐chain 13 | Cytoplasm | 1.1 | 0.548 | −28.3 | 0.008 |
| P18669_PGAM1 | Phosphoglycerate mutase 1 | Cytoplasm | 1.6 | 0.841 | 2.9 | 0.008 |
| Q9UKS6_PACN3 | Protein kinase C and casein kinase substrate in neurons protein 3 | Cytoplasm | 2.6 | 0.095 | 12.8 | 0.016 |
| Q13418_ILK | Integrin‐linked protein kinase | Cytoplasm | 2.1 | 0.690 | 18.2 | 0.016 |
| P11177_ODPB | Pyruvate dehydrogenase E1 component subunit beta | Mitochondrion | 1.2 | 0.690 | 1.7 | 0.016 |
| P09622_DLDH | Dihydrolipoyl dehydrogenase | Mitochondrion | 1.3 | 1.000 | 2.4 | 0.008 |
| P31937_3HIDH | 3‐hydroxyisobutyrate dehydrogenase | Mitochondrion | 2.0 | 0.310 | 3.4 | 0.008 |
| P82909_RT36 | 28S ribosomal protein S36, mitochondrial | Mitochondrion | 1.7 | 0.421 | 2.3 | 0.008 |
| P30049_ATPD | ATP synthase subunit delta | Mitochondrion | 1.1 | 0.690 | −3.0 | 0.008 |
| P36776_LONM | Lon protease homologue | Mitochondrion | −4.4 | 0.032 | −5.5 | 0.008 |
| O00159_MYO1C | Nuclear myosin 1 (NM1) | Nucleus | 4.8 | 0.016 | 2.5 | 1.000 |
| P28289_TMOD1 | Tropomodulin‐1 | Erythrocyte cytoplasm | 1.7 | 0.548 | 3.2 | 0.008 |
| Q9H7C9_CK067 | Mth938 domain‐containing protein | Adipocyte cytoplasm | 4.0 | 0.310 | 7.6 | 0.008 |
| P02743_SAMP | Serum amyloid P‐component | Extracellular space | −1.1 | 0..151 | −4.6 | 0.008 |
| P04217_A1BG | Alpha‐1B‐glycoprotein | Extracellular space | 2.6 | 0.421 | 5.6 | 0.008 |
| P14543_NID1 | Nidogen‐1 | Extracellular space | −1.6 | 0.222 | −2.7 | 0.016 |
| Q9GZM7_TINAL | Tubulointerstitial nephritis antigen‐like | Extracellular space | −2.2 | 0.222 | −5.3 | 0.016 |
| P01834_IGKC | Ig kappa chain C region | Extracellular space | 2.8 | 0.016 | 2.2 | 0.095 |
Difference >1.5‐fold change and P<0.025 (Mann–Whitney U test followed by Bonferroni's correction) was considered significant. Fold‐change values indicate higher (+) and lower (−) intensity levels in AMI samples compared with controls. AMI indicates acute myocardial infarction.