Table 2.

Predictors of Cardiometabolic Biomarker Values After 12 and 24 Months of Weight Loss Study Participation

	Models Predicting 12‐Month Biomarker Values (n=406)
	Insulin (R2=0.37)	Cholesterol (R2=0.46)	Glucose (R2=0.26)	TG (R2=0.66)	CRP (R2=0.16)
Baseline level of biomarker	0.551**	0.597**	0.786**	0.752**	0.470**
Baseline weight	−0.057	−0.093	0.069	0.286	0.041
Percent change in weight	0.274**	0.403*	0.351**	1.514**	0.091*
Baseline waist	0.294	0.409	0.211	−0.585	0.013
Age	−0.025	0.520	0.016	0.301	−0.021
White race/ethnicity	−2.022	5.980	−0.964	1.428	−0.420
Dietary intervention	0.0033	−1.380	−0.597	−5.874*	−0.167
Step‐test heart rate	−0.036	0.071	0.058	−0.053	−0.008
Waist‐to‐height ratio	−24.329	−72.124	−24.980	95.266	4.740

	Models Predicting 24‐Month Biomarker Values (n=383)
	Insulin (R2=0.52)	Cholesterol (R2=0.39)	Glucose (R2=0.31)	TG (R2=0.56)	CRP (R2=0.07)
Baseline level of biomarker	0.770**	0.505**	0.525**	1.150**	0.430*
Baseline weight	0.073	−0.300	0.104	0.673	−0.060
Percent change in weight	0.399**	0.544*	0.406**	1.788**	0.064
Baseline waist	−0.173	0.847	−0.306	−2.147	−0.029
Age	0.067	0.637**	0.064	0.817	−0.098
White race/ethnicity	−0.744	5.592	−1.137	−3.287	−2.545
Dietary intervention	0.264	−2.682	0.423	−6.210	0.917
Step‐test heart rate	0.001	0.277	0.069	−0.324	0.872
Waist‐to‐height ratio	31.76	−127.74	31.81	211.26	0.829

CRP indicates C‐reactive protein; TG, triglycerides.

*P<0.01, **P<0.001. Values shown are β coefficients in a regression model for each biomarker during each period.