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. Author manuscript; available in PMC: 2014 Nov 15.
Published in final edited form as: Semin Immunol. 2013 Nov 15;25(4):10.1016/j.smim.2013.10.022. doi: 10.1016/j.smim.2013.10.022

Figure 1. Th and CTL Lineage-commitment in the thymus.

Figure 1

The reciprocal action and counter action of the master transcription factors, ThPOK and Runx3, drive the Th-lineage- and CTL-lineage commitment of MHC class II and MHC class I restricted thymocytes, respectively.