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. 2013 Jul 25;2(3):186–207. doi: 10.3390/microarrays2030186

Table 1.

Representative studies examining gene expression in the inner ear during development, in different cell/tissue types and following trauma.

Reference Organism and organ Methodology Developmental stage or treatment
Developmental differences in gene expression
[38] Mouse cochlea Affymetrix GeneChip oligonucleotide array P2 and P32
[39] Mouse cochlea Affymetrix GeneChip oligonucleotide array P2 and P32
[40] Mouse cochlea-conditionally immortal cell line Affymetrix GeneChip oligonucleotide array 14 days following differentiation
[41] Mouse inner ear Affymetrix GeneChip oligonucleotide array E9-E15
[42] Mouse cochlea Affymetrix GeneChip oligonucleotide array P3 and adult
Cell/Tissue differences in gene expression
[27] Chick cochlea and utricles Custom built cDNA and oligonucleotide arrays cochlea versus utricles
[28] Rat cristae ampullaris Agilent RNA6000 Nano Lab Chip hair cells versus supporting cells
[41] Mouse inner ear Affymetrix GeneChip oligonucleotide array cochlea, utricle, or saccule
[24] Chick inner ear Custom built TF oligonucleotide array 30 min and 1, 2, 3 h post-ototoxic or laser trauma
[43] Zebrafish lagena Affymetrix GeneChip oligonucleotide array hair cells versus liver hepatocytes
Gene expression during regeneration following trauma
[24] Chick inner ear Custom built TF oligonucleotide array 30 min and 1, 2, 3 h post-ototoxic or laser trauma
[25] Zebrafish inner ear Agilent Zebrafish oligonucleotide arrays 2 and 4 days post-acoustic trauma
[44] Zebrafish inner ear Illumina tag profiling (SAGE) 0, 1, 2, 4 days post-acoustic trauma