Table 3. Relationships between the probability of dogs being infectious to sandflies and immunologic, parasitological or clinical parameters.
Variable | n | OR | P | r2 | AUC |
Time since infection (days) | 103 | 1.003 | 0.0369 | 0.044 | 0.649 |
Anti-Leishmania antibody1 | 103 | 5.685 | 0.0001 | 0.296 | 0.857 |
Total clinical score | 93 | 1.285 | 0.0003 | 0.138 | 0.729 |
Dermatitis score | 93 | 1.492 | 0.0006 | 0.127 | 0.708 |
Other clinical score | 93 | 1.376 | 0.0065 | 0.079 | 0.672 |
PCR | 103 | 26.1 | 0.002 | 0.248 | 0.712 |
Bone marrow load1 | 103 | 2.224 | 0.0001 | 0.258 | 0.837 |
Ear skin load1 | 58 | 2.78 | 0.0001 | 0.488 | 0.937 |
The probability of being infectious to sandflies measured by xenodiagnosis of infected dogs. OR odds ratio; r2 logistic regression pseudo; AUC area under receiver operator curve; dermatitis score: score of clinical dermatitis in skin only; PCR: negative or positive by standard PCR;
1log10 transformed anti-Leishmania antibody units (per mL) measured by ELISA, and L. infantum numbers in bone marrow (per mL), and ear skin biopsies (per gram), measured by qPCR.