Table 1. Fixed model parameters and parameters estimated from the best-fit model for typhoid inpatients at Christian Medical College hospital in Vellore, India.

Fixed parameters
Parameter definition	Symbol	Value	Source
Birth rate	B	14.9–19.2 live births per 1,000	Census data
Natural mortality rate	μ	7.2–8.2 deaths per 1,000	Census data
Duration of infectiousness	1/δ	4 weeks	[36]
Fraction infected who become chronic carriers	θ	0.003–0.101 depending on age	[33]
Disease-induced mortality	α	0.001	Assumption, [1]
Duration of temporary full immunity to infection	1/ω	104 weeks	Assumption*, [30]
Rate of shedding into the water supply	γ	1 infectious unit/week	Assumption†
Rate of decay of infectious particles from water supply	ξ	1/3 week−1	[37]

The best-fit model was not sensitive to this parameter.

Inseparable from the estimated long-cycle transmission parameter, β_w.