Table 1. Baseline characteristics according to race ethnicity.
Sociodemographic factors | Whole cohort | Hispanic | Non-Hispanic White | Non-Hispanic Black | P-value§ |
N | 1946 | 1059 | 381 | 425 | |
Age, mean ± SD (years) | 69±10 | 66±9 | 73±10 | 72±11 | <0.0001 |
Female sex, n (%) | 1253 (64%) | 682 (64%) | 237 (61%) | 300 (70%) | 0.02 |
Education (High School graduate), n (%) | 856 (44%) | 222 (21%) | 328 (85%) | 266 (62%) | <0.0001 |
Vascular risk factors | |||||
Hypertension*, n (%) | 1447 (74%) | 813 (76%) | 253 (65%) | 350 (82%) | <0.0001 |
Systolic blood pressure, mean ± SD (mmHG) | 144±20 | 143±21 | 140±20 | 148±21 | <0.0001 |
Coronary heart disease, n (%) | 429 (22%) | 218 (20%) | 101 (26%) | 97 (23%) | 0.06 |
Diabetes mellitus, n (%) | 467 (24%) | 282 (26%) | 56 (15%) | 121 (28%) | <0.0001 |
Waist circumference, mean ± SD | 36.8±4.9 | 37±5 | 36±5 | 37±5 | 0.006 |
Any physical activity, n (%) | 1067 (55%) | 521 (49%) | 250 (64%) | 261 (61%) | <0.0001 |
Past smoker, n (%) | 674 (35%) | 344 (32%) | 158 (41%) | 150 (35%) | <0.0001 |
Current smoker, n (%) | 347 (18%) | 179 (17%) | 56 (14%) | 103 (24%) | <0.0001 |
Moderate alcohol consumption**, n (%) | 647 (33%) | 322 (30%) | 165 (43%) | 139 (32%) | <0.0001 |
Laboratory measurements | |||||
LpPLA2, mean ± SD (mass, ng/ml) | 308.7±88.2 | 300.2±84.9 | 349.6±82.4 | 294.9±90.8 | <0.0001 |
LpPLA2, mean ± SD (activity, nmol/min/mL) | 116.9+29.6 | 114±27.7 | 131.4±31.0 | 109.1±28.1 | <0.0001 |
HDL, mean ± SD (mg/dL) | 46.5±14.2 | 43.5±12.9 | 48.6±14.3 | 51.1±15.2 | <0.0001 |
LDL, mean ± SD (mg/dL) | 129.2±35.5 | 129. 5±34.8 | 132.7±34.2 | 125.5±37.6 | 0.02 |
SD: standard deviation; IQR: interquartile range.
Hypertension defined as: history, taking medications, or systolic blood pressure ≥140 mmHg, or diastolic blood pressure ≥90 mmHg;
Moderate alcohol intake: 1 alcoholic drink per week to 2 drinks per day.
Kruskal Wallis test for continuous variables and Chi-Squared test for categorical variables.