Table 1. Uni- and multivariate analysis of MFS in the luminal BC public data.
Univariate | Multivariate | ||||||
N | HR [95CI] | p | N | HR [95CI] | p | ||
Age | >50 vs < = 50 y | 512 | 1.03 [0.73–1.46] | 0,87 | |||
pT | pT2-3 vs pT1 | 556 | 1.76 [1.25–2.48] | 1,30E-03 | 509 | 1.51 [1.05–2.18] | 2,65E-02 |
pN | pos vs neg | 829 | 1.21 [0.9–1.63] | 0,22 | |||
SBR grade | 2–3 vs 1 | 650 | 2.72 [1.69–4.4] | 4,22E-05 | 509 | 1.39 [0.82–2.34] | 0,22 |
Histology ** | ILC vs IDC | 128 | 1.45 [0.59–3.56] | 0,41 | |||
other vs IDC | 128 | 0.78 [0.18–3.29] | 0,73 | ||||
Hormone therapy | Yes vs No | 746 | 0.64 [0.45–0.93] | 2,01E-02 | 509 | 0.68 [0.41–1.12] | 0,13 |
Chemotherapy | Yes vs No | 749 | 1.08 [0.71–1.66] | 0,71 | |||
ERBB2 IHC status | pos vs neg | 148 | 1.19 [0.36–3.91] | 0,77 | |||
Molecular subtype * | LumB vs lumA | 1016 | 2.07 [1.67–2.57] | 3,99E-11 | 509 | 2.53 [1.66–3.87] | 1,66E-05 |
RECQL4 | 1016 | 1.55 [1.37–1.75] | 1,44E-12 | 509 | 1.33 [1.02–1.73] | 3,40E-02 |
as previously defined [4].
IDC: infiltrated ductal carcinomas; ILC: infiltrated lobular carcinomas.