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. 2014 Jan 9;9(1):e84986. doi: 10.1371/journal.pone.0084986

Table 1. Replication index (RI) of listeria strains in CaCo-2 cells in presence of TiO2 NPs.

Strains + Ti02 NPs (µg/ml) Replication Index
LM2+0 1.55±0.1
LM2+0.08 1.45±0.3
LM2+0.8 1.22±0.4
LM2+8 0.8±0.3
LM2+80 0.75±0.4*
LM9+0 11.12±0.2
LM9+0.08 11.4±0.3
LM9+0.8 11.2±0.5
LM9+8 10.57±0.3
LM9+80 5.41±0.1***

Replication index: Intracellular growth was expressed as replication index (RI) which corresponds to the number of CFU 3 hrs post-infection divided by the number of CFU 1 hr post-infection. Data are presented as means (± standard deviation) of at least three experiments. Asterisks indicate statistically significant values compared to control bacterial cells (*p<0.05; ***p<0.001).