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. 2014 Jan 9;9(1):e85545. doi: 10.1371/journal.pone.0085545

Figure 2. Transactivation of CCND2 promoter is regulated by FOXL2, GATA4, and SMAD3.

Figure 2

Relative luciferase activity was measured in KGN cells after transfection with CCND2 luciferase promoter construct together with wild type or C134W-mutated FOXL2 in the presence or absence of GATA4 and SMAD3 over-expression. CCND2 promoter activity was measured 24 h after transfection; at least three independent experiments were performed in triplicate. Bars not connected by the same letter are significantly different. P<0.05.