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. 2014 Jan 9;9(1):e85545. doi: 10.1371/journal.pone.0085545

Figure 3. Wt FOXL2 reduces viable cell number, and GATA4 protects GCT cells from wt FOXL2 induced apoptosis.

Figure 3

KGN cells were transfected with wild type FOXL2, C134W mutated FOXL2, GATA4, and SMAD3 expression plasmids. A) The cell viability was measured 48 h after transfection. B) The activated caspase 3/7 was measured 24 h after transfection. Viable cell number and Caspase 3/7 activity are presented relative to control transfection as the mean ± SEM of at least three independent experiments performed in triplicate. Bars not connected by the same letter are significantly different. P<0.05.