Infant Postcircumcision bleeding Birth cephalohematoma Umbilical stump bleeding or delayed stump separation Postvenipuncture bleeding Macroscopic hematuria Petechiae at clothing line pressure sites Bruising at sites of object pressure, such as infant car seat fasteners Index child or family members Spontaneous, easy or excessive bruising Mucocutaneous bleeding (eg, gingival bleeding) Epistaxis that is spontaneous, lasts >10 min or requires medical treatment Bleeding from minor wounds that lasts >15 min or recurs within seven days Prolonged bleeding after surgical procedures Bruises with palpable lumps beneath them Joint swelling with minor injury Blood in the stool or urine Menorrhagia Unexplained anemia History of blood transfusion

Adapted from references 33,37