Table 4. Non-structural gene substitution rate variation among viruses with different cell tropisms.

	N	L	H	Ep
N	-	0.99	0.99	1.00
L	0.007	-	0.56	1.00
H	0.009	0.44	-	1.00
Ep	0.0006	0.0001	0.0001	-

The significance of viruses with each target cell in the left column having higher log scale mean substitution rates than the viruses with each target cell in the top row is designated with a p-value from a one-tailed t-test. The threshold for statistical significance (α = 0.01) was Bonferroni-corrected to account for multiple comparisons (P<0.002); the significant values are bolded. N = neurons, L = leukocytes, H = hepatocytes, Ep = epithelial cells.