Table 2. Characteristics of regulator groups.
Low regulators (n = 14) | High regulators (n = 16) | Low vs. high regulators | |
Median (IQ range) | Median (IQ range) | p* | |
Age (years) | 43 (39–49) | 40 (30–52) | 0.755 |
Time HIV seropositive (months) | 65 (16–100) | 52 (21–68) | 0.510 |
CD4+ T cell count (×106/l) | 488 (438–565) | 392 (225–825) | 0.262 |
CD8+ T cell count (×106/l) | 1458 (880–2148) | 938 (663–1261) | 0.031 |
HIV-RNA in plasma (copies/ml) | 17000 (670–52000) | 43000 (4000–135000) | 0.220 |
Annual CD4 T cell count loss (cells ×106/l) | −10 (−75–41) | 62 (−46–235) | 0.056 |
β2-microglobulin in serum (mg/l) | 2.5 (2.1–3.0) | 2.3 (1.5–5.3) | 0.965 |
CD38 on CD8+ T cells (molecules/cell) | 1894 (1770–7116) | 4271 (1688–11165) | 0.244 |
CD38 on CD8+CD38+PD-1+ T cells (molecules/cell) | 2541 (1938–8101) | 4946 (1962–13798) | 0.228 |
LPS (pg/µl) | 70 (57–76) | 70 (59–92) | 0.693 |
Comparisons between patient groups, p<0.05 bolded, p<0.10 italic.