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. 2014 Jan 10;3:116. doi: 10.3389/fcimb.2013.00116

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Copyright © 2014 Kim and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Role of DUOX in diverse biological activities. In addition to its original function in redox-dependent antimicrobial defense in mucosa described in Figures 1, 2. DUOX system is also involved in cross-linking of biomolecules, intestinal epithelial cell renewal, redox-dependent modulation of signaling pathways, and wound healing in different metazoans. See text for more details.