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Effects of chemotherapeutic agents on downstream pathways. Cell lysates were prepared from OVCA429, HEY and TOV21G cells treated with cisplatin (Cis) or paclitaxel (Pac) as indicated, and subjected to western blot analysis with anti-phospho-STAT3, anti-STAT3 and anti-GAPDH (A), anti-phospho-ERK, anti-ERK, anti-phospho-AKT, anti-AKT and anti-GAPDH (B), or anti-MDR1, anti-GST-pi, anti-ERCC1 and anti-GAPDH (C).
