Table 3. Brief description of patients with nodal metastasis falsely classified as low risk.
Characteristics | Patient 1 | Patient 2 | Patient 3 | Patient 4 |
---|---|---|---|---|
Preoperative assessment | ||||
Age, years | 62 | 47 | 46 | 32 |
FIGO stage | IB1 | IB1 | IB1 | IB1 |
Histology | Squamous | Squamous | Squamous | Squamous |
Serum SCC Ag (ng ml−1) | 0.83 | 0.35 | 1.4 | 0.9 |
Tumour size by MRI (cm) | 2 | 0a | 0a | 0a |
PM invasion by MRI | Absent | Absent | Absent | Absent |
LNM by PET/CT |
Absent |
Absent |
Absent |
Absent |
Postoperative assessment | ||||
Histology | Squamous | Squamous | Squamous | Squamous |
Tumour size (cm) | 4.0 | 1.5 | 1.5 | 1.3 |
Depth of stromal invasion (mm) | 6 | 2 | 10 | 6 |
LVSI | Present | Absent | Present | Present |
PM invasion | Present | Absent | Absent | Absent |
LNM | Yes (1 of 34) | Yes (1 of 25) | Yes (1 of 18) | Yes (4 of 42) |
Location of metastatic LN | Left external | Right external | Right internal | Left obturator Right external |
Largest diameter of metastatic LN | 0.7 mm | 6 mm | <1 mm | 7 mm |
Para-aortic LNM | No (0 of 1) | NA | No (0 of 1) | No (0 of 1) |
Adjuvant treatment | CCRTb | CCRTb | CCRTb | CCRTb |
Recurrence | No | No | No | No |
Progression-free survival | 21 months | 32 months | 6 months | 40 months |
Abbreviations: FIGO=International Federation of Gynecology and Obstetrics; LN=lymph node; LNM=LN metastasis; LVSI=lymphovascular space invasion; MRI=magnetic resonance imaging; NA, not applicable; PET/CT=positron emission tomography/computed tomography; PM=parametrial; SCC Ag=squamous cell carcinoma antigen.
No visible residual tumour in the uterine cervix.
Concurrent chemoradiation (weekly cisplatin regimen).