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. 2013 Nov 14;110(1):34–41. doi: 10.1038/bjc.2013.718

Table 3. Brief description of patients with nodal metastasis falsely classified as low risk.

Characteristics Patient 1 Patient 2 Patient 3 Patient 4
Preoperative assessment
Age, years 62 47 46 32
FIGO stage IB1 IB1 IB1 IB1
Histology Squamous Squamous Squamous Squamous
Serum SCC Ag (ng ml−1) 0.83 0.35 1.4 0.9
Tumour size by MRI (cm) 2 0a 0a 0a
PM invasion by MRI Absent Absent Absent Absent
LNM by PET/CT
Absent
Absent
Absent
Absent
Postoperative assessment
Histology Squamous Squamous Squamous Squamous
Tumour size (cm) 4.0 1.5 1.5 1.3
Depth of stromal invasion (mm) 6 2 10 6
LVSI Present Absent Present Present
PM invasion Present Absent Absent Absent
LNM Yes (1 of 34) Yes (1 of 25) Yes (1 of 18) Yes (4 of 42)
Location of metastatic LN Left external Right external Right internal Left obturator Right external
Largest diameter of metastatic LN 0.7 mm 6 mm <1 mm 7 mm
Para-aortic LNM No (0 of 1) NA No (0 of 1) No (0 of 1)
Adjuvant treatment CCRTb CCRTb CCRTb CCRTb
Recurrence No No No No
Progression-free survival 21 months 32 months 6 months 40 months

Abbreviations: FIGO=International Federation of Gynecology and Obstetrics; LN=lymph node; LNM=LN metastasis; LVSI=lymphovascular space invasion; MRI=magnetic resonance imaging; NA, not applicable; PET/CT=positron emission tomography/computed tomography; PM=parametrial; SCC Ag=squamous cell carcinoma antigen.

a

No visible residual tumour in the uterine cervix.

b

Concurrent chemoradiation (weekly cisplatin regimen).