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. 2013 Nov 21;110(1):55–62. doi: 10.1038/bjc.2013.721

Figure 1.

Figure 1

Patient disposition flow diagram. aAll screened patients. Used to calculate the correlation between clinical characteristics and tumour EGFR mutation status and the comparison of EGFR mutation status between tumour DNA and plasma-derived circulating free DNA. bOne patient of EGFR mutation-positive-ineligible status was treated in error and included in the evaluable-for-safety population. A total of 107 patients therefore started study treatment. cFull analysis set population. Used to summarise efficacy data, and for the comparison of EGFR mutation status in plasma and tumour samples. dNumber of patients with EGFR mutation-positive tumours (n=118) used as the denominator for the percentage calculation. eNumber of patients started on treatment (n=107) used as the denominator for the percentage calculation. Abbreviation: EGFR=epidermal growth factor receptor.