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. 2014 Jan 10;7:80. doi: 10.3389/fnint.2013.00080

Table 1.

Pericyte markers in health and disease.

Pericyte marker/location Main function Main physiological role Health Disease Reference
PDGFRβ/cell surface protein Tyrosine-protein kinase; Kinase receptor Embryonic development, proliferation, chemotaxis, host-virus interaction + +/- Fibrosis Tumor Blood–brain barrier disruption Song et al. (2005), Armulik et al. (2010), Dore-Duffy and Cleary (2011)
αSMA/Filament protein Contractility Regulation of blood flow and motility - ++ Fibrosis Tumor Blood–brain barrier disruption Song et al. (2005), Dore-Duffy and Cleary (2011)
NG2/cell surface protein Cell adhesion protein Vasculo-genesis + +Fibrosis Tumor Blood–brain barrier disruption Ozerdem et al. (2002), Dore-Duffy and Cleary (2011)
RGS-5/intracellular protein GTPase-activating protein Cell motility + ++ Fibrosis Tumor Blood–brain barrier disruption Song et al. (2005), Dore-Duffy and Cleary (2011)
Desmin/filament protein Contractility Regulation of blood flow and motility + + Fibrosis Tumor Blood–brain barrier disruption Dore-Duffy and Cleary (2011), Kamouchi et al. (2011)
CD13/cell surface protein Ectopeptidase Pericyte differentiation + ++ Fibrosis Tumor Blood–brain barrier disruption Armulik et al. (2010), Kamouchi et al. (2011)

Symbols are as follow: (+) Indicates that the marker is present; (-) indicates that the marker is absent; (+/-) indicates a decrease in marker expression and; (++) indicates that the marker is over expressed.