Table 2.
Features and Outcome of Graves' Ophthalmopathy in 65 Untreated Patients at First and Last Observations
| Feature | First observation | Last observation | p |
|---|---|---|---|
| Exophthalmometry (most prominent eye) |
20 mm (IQR: 18–22; range: 17–24) |
20 mm (IQR: 19–22; range: 17–24) |
0.62 |
| Eyelid aperture (most affected eye) |
11 mm (IQR: 10.2–13; range: 7–15) |
11 mm (IQR: 10–13; range: 8–15) |
0.10 |
| CAS |
2 (IQR: 1–3; range: 0–6) |
1 (IQR: 0–2; range: 0–5) |
<0.0001 |
| Diplopia |
Absent: 49 |
Absent: 54 |
0.21 |
| |
Intermittent: 5 |
Intermittent: 3 |
|
| |
Inconstant: 11 |
Inconstant: 6 |
|
| |
Constant: 0 |
Constant: 0 |
|
| Visual acuity (most affected eye) |
9.9±0.1/10 (range: 9–10) |
9.9±0.2/10 (range: 9–10) |
0.08 |
| NOSPECS score |
2 (IQR: 1–3; range: 1–4) |
1 (IQR: 1–3; range: 1–4) |
0.01 |
| GO outcome |
Improved: 33 (50.8%) |
n/a |
|
| |
Stable: 22 (33.8%) |
||
| Worsened: 10 (15.4%) | |||
Numerical values are reported as median, with the exception of visual acuity (mean±SD). p Values were obtained by paired sign, with the exception of visual acuity (paired t-test) and diplopia (Fisher's exact test). Significant p values are presented in boldface.
CAS, Clinical Activity Score.