Table 2.
Comparison between Baseline and Follow-up Symptom Scores (N=36)
| ESAS symptoms | Total no. of patients | SRRa n (%) | Baseline median (IQR, P25–P75) | Follow-up median (IQR, P25–P75) | Z statistic | P* |
|---|---|---|---|---|---|---|
| TSDS |
36 |
NA |
34.00 (29.00 – 40.75) |
26.50 (23.25 – 32.75) |
−6.895 |
<0.001 |
| Fatigue |
36 |
9 (25.0) |
4.50 (3.25 – 7.00) |
4.00 (3.00 – 6.00) |
−2.846 |
0.004 |
| Pain |
36 |
11 (30.6) |
6.00 (0.00 – 7.00) |
4.00 (0.00 – 6.00) |
−3.690 |
<0.001 |
| Anxiety |
36 |
13 (36.1) |
4.00 (3.00 – 6.00) |
3.50 (1.25 – 4.00) |
−3.523 |
<0.001 |
| Well-being |
36 |
8 (22.2) |
4.00 (0.00 – 6.00) |
3.00 (0.00 – 4.00) |
−4.148 |
<0.001 |
| Depression |
36 |
9 (25.0) |
4.00 (3.00 – 6.00) |
3.00 (0.00 – 5.00) |
−1.640 |
0.038 |
| Dyspnea |
36 |
8 (22.2) |
4.00 (3.00 – 5.00) |
3.00 (0.25 – 4.00) |
−3.815 |
<0.001 |
| Drowsiness |
36 |
3 (8.3) |
4.00 (0.00 – 4.00) |
3.00 (0.00 – 4.00) |
−3.231 |
0.001 |
| Appetite |
36 |
3 (8.3) |
3.00 (0.00 – 4.75) |
3.00 (0.00 – 4.00) |
−2.919 |
0.004 |
| Nausea | 36 | 4 (11.1) | 3.00 (0.00 – 4.00) | 3.00 (0.00 – 3.00) | −3.350 | 0.001 |
a
Defined as a two-point decrease or more in 0–10 score on individual symptoms on the ESAS; NA not analyzed.
*
Wilcoxon signed-rank test.
ESAS, Edmonton Symptom Assessment Scale; IQR, interquartile range; SRR, symptom response rate; TSDS, total symptom distress score.