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. 2014 Jan 10;20(2):267–280. doi: 10.1089/ars.2012.4616

FIG. 2.

FIG. 2.

PV relationships in WT and MAO-B−/− mice. (A) Representative PV loops from WT and MAO-B−/− at baseline (dashed line) and 9 weeks after TAC (full line). (B) Morphological and functional changes determined via PV relationships in WT (white bars) and MAO-B−/− (black bars) mice at baseline (n=6 each group) and after 9 weeks of TAC (n=8 each group). *p<0.05 versus sham, †p<0.01 versus WT T9w, ‡p<0.01 versus WT sham, §p=0.053 versus WT sham. LVP, left ventricular pressure; LVV, left ventricular volume; PV, pressure-volume; EDV, end-diastolic volume; ESV, end-systolic volume; EF, ejection fraction; dP/dtmax, an index of myocardial contractility; dP/dtmin, an index of relaxation; PRSW, preload-recruitable stroke work, index of contractility.