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. Author manuscript; available in PMC: 2014 Nov 27.
Published in final edited form as: Tetrahedron Lett. 2013 Nov 27;54(48):10.1016/j.tetlet.2013.09.107. doi: 10.1016/j.tetlet.2013.09.107

Table 3.

Comparison of microwave-assisted synthesis of tetrahydroquinoline under standard reaction conditions.

graphic file with name nihms529470u1.jpg
Compound R1 R2 Microwave Heating Conventional heating
Time Yield (%) Time Yield (%)
3 graphic file with name nihms529470t1.jpg p-SO2NH2 10 min 60 48 h 22 (ref:7)
4 graphic file with name nihms529470t2.jpg p-SO2NH2 15 min 66 24 h 2 (ref:7)
5 graphic file with name nihms529470t3.jpg p-SO2NH2 15 min 90 24 h 20 (ref:7)
6 graphic file with name nihms529470t4.jpg p-SO2NH2 10 min 61 48 h 19 (ref:7)
7 graphic file with name nihms529470t5.jpg p-SO2NH2 15 min 67 24 h 30 (ref:6)
8 graphic file with name nihms529470t6.jpg p-SO2NH2 15 min 66 12 h 13 (ref:7)
9 graphic file with name nihms529470t7.jpg p-SO2NH2 15 min 67
10 graphic file with name nihms529470t8.jpg o-SO2NH2 15 min 55
11 graphic file with name nihms529470t9.jpg p-COCH3 15 min 74 2 h 98 (ref: 3)
12 graphic file with name nihms529470t10.jpg p-SO2NH2 15 min 40
13 graphic file with name nihms529470t11.jpg p-OMe 10 min 58
14 graphic file with name nihms529470t12.jpg p-Br 10 min 56
15 –H p-SO2NH2 15 min 48
16 graphic file with name nihms529470t13.jpg p-COOH 15 min 65