Figure 2.

Tissue-specific expression effects of reversed parent-of-origin sex chromosome inheritance. Shown are the distributions of parent-of-origin effects for genes expressed specifically in the testes, the adult midgut, and all other genes. (A) Log2 expression differences between X_MY_P and X_PY_M males. The median fold-change of all three groups of genes is significantly different from zero (testis-specific genes = 0.24; midgut-specific genes = −0.23; all other genes = −0.03; P_MW < 0.0001 in all three cases). (B) Log2 expression differences between XY_MY_P and XY_PY_M males. The median fold-change of all three groups of genes is significantly different from zero (testis-specific genes = 0.22; midgut-specific genes = −0.36; all other genes = −0.02; P_MW < 0.0001 in all three cases).