Table 2.
Results according to population | GWAS results (p-value < 0.01) | Functional prioritization (fpp-value < 0.05) |
---|---|---|
CEU | ||
No. of SNPs (loci) | 24,719 | 4,086 |
No. of gene expression patterns | 1,938* | 453** |
Mode of SNP-gene regulation | ||
Cis | 1,938 | - |
Trans | - | 4,086 |
YRI | ||
No. of SNPs (loci) | 34,395 | 6,996 |
No. of gene expression patterns | 3,289* | 419** |
Mode of SNP-gene regulation | ||
Cis | 3,289 | 8 |
Trans | - | 6,988 |
Number of genes corresponding to loci selected in GWAS
Number of phenotype-related genes that were regulated by prioritized loci, as assessed using the fpp-value approach