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. 2012 Mar 28;33(4):351–361. doi: 10.1007/s10059-012-2264-7

Table 2.

Functional prioritization results of the fpp-value approach

Results according to population GWAS results (p-value < 0.01) Functional prioritization (fpp-value < 0.05)
CEU
  No. of SNPs (loci) 24,719 4,086
  No. of gene expression patterns 1,938* 453**
  Mode of SNP-gene regulation
    Cis 1,938 -
    Trans - 4,086
YRI
  No. of SNPs (loci) 34,395 6,996
  No. of gene expression patterns 3,289* 419**
  Mode of SNP-gene regulation
    Cis 3,289 8
    Trans - 6,988
*

Number of genes corresponding to loci selected in GWAS

**

Number of phenotype-related genes that were regulated by prioritized loci, as assessed using the fpp-value approach