Fig. 1.
Effects of gintonin on INMDA. (A) A representative trace of gintonin (1 μg/ml) (GT)-mediated potentiation of INMDA in oocytes expressing the rat NMDA receptor. The trace represents 6 separate oocytes. (B) Concentration-dependent effect of gintonin on INMDA potentiation. The trace represents 6 separate oocytes. Application of NMDA (300 μM) and glycine (10 μM) elicited INMDA. Gintonin application after NMDA (300 μM) and glycine (10 μM) potentiated INMDA. (C) Concentration-dependent potentiating effects of gintonin on INMDA. Oocytes were voltage-clamped at a holding potential of −60 mV. Each point represents the mean ± SEM (n = 4–5/group).