Differential Bcl-2 expression in mouse retina after multiple BSO administration. (A) Immunohistochemical analysis of Bcl-2 expression in mouse retina under multiple BSO administration condition. Immunoreactivity intensities were determined by NIH ImageJ. Scale bar represents 1 mm. (B) Immunohistochemical analysis of Bcl-2 expression in mouse retina layers under multiple BSO administration condition. Immunoreactivities were determined from at least 10 retina tissue sections of 6 eyeballs (3 animals). PCL, ONL, OPL, INL, IPL, and GCL represent photoreceptor cell layer, outer nuclear layer, outer plexiform layer, inner nuclear layer, inner plexiform layer, and ganglion cell layer, respectively. Statistical significances are indicated as *p < 0.05, **p < 0.01 and ***p < 0.001 (one-way ANOVA).