Table 1.
Protein | Outcome of FAK interaction | DNA binding | Reference |
---|---|---|---|
p53* | Degradation | + | Lim et al. (2008a) |
mdm-2* | p53 ubiquitination | − | Lim et al. (2008a) |
GATA4 | Degradation | + | Lim et al. (2012) |
CHIP | GATA4 ubiquitiantion | − | Lim et al. (2012) |
MBD2 | Dissociation from HDAC1 | + | Luo et al. (2009) |
Enhance myogenin transcription |
Pyk2 also interacts with p53 and mdm-2 (Lim et al., 2010a).