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. 2013 May 16;36(1):1–6. doi: 10.1007/s10059-013-0139-1

Table 1.

Nuclear FAK interacting proteins

Protein Outcome of FAK interaction DNA binding Reference
p53* Degradation + Lim et al. (2008a)
mdm-2* p53 ubiquitination Lim et al. (2008a)
GATA4 Degradation + Lim et al. (2012)
CHIP GATA4 ubiquitiantion Lim et al. (2012)
MBD2 Dissociation from HDAC1 + Luo et al. (2009)
Enhance myogenin transcription
*

Pyk2 also interacts with p53 and mdm-2 (Lim et al., 2010a).