Figure 6.

The influence of IBMX on the rate of pH recovery. BCEFC-loaded NPE cells were subjected to an episode of acidification by exposure for 5 minutes to Krebs solution containing 20 mM ammonium chloride; then the rate of cytoplasmic pH recovery was measured. One group of cells was superfused throughout the experiment with CO₂/HCO₃⁻-buffered Krebs solution containing IBMX (500 μM), and a second group was superfused with control CO₂/HCO₃⁻-buffered Krebs solution. The results are the mean ± SEM of five to seven individual experiments. **Significant difference from the control group, P < 0.001.