Table II.
Newly diagnosed patients with AML (cohort 1): characteristics of responders versus non-responders.
| CR | NR | |
|---|---|---|
| Total | 21 (40.4%) | 31 (59.6%) |
| Overall survival (days) | 481 | 206 |
| Median age, years (range) | 74 (45–86) | 77 (60–91) |
| Adverse cytogenetics (n = 18) | 6 (33.3%) | 12 (66.7%) |
| WBC > 15 × 103/μL (n = 10) | 3 (30%) | 7 (70%) |
| Prior HMA (n = 6) | 0 | 6 (100%) |
AML, acute myeloid leukemia; CR, complete response; NR, no response; WBC, white blood cell count; HMA, hypomethylating agent therapy, azacitidine or decitabine.