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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Neuropharmacology. 2013 Sep 30;77:224–233. doi: 10.1016/j.neuropharm.2013.09.019

TABLE 2.

Δ FosB expression measured by immunoblot in brains from vehicle- and THC-treated mice

Region Δ FosB-ir Integrated intensity
VEHICLE THC
Prefrontal cortex 2.94 ± 0.33 4.20 ± 0.47*
Nucleus accumbens 1.81 ± 0.22 3.39 ± 0.25***
Caudate-putamen 1.56 ± 0.11 2.52 ± 0.12***
Lateral amygdala 2.94 ± 0.11 4.05 ± 0.08*
Basomedial amygdala 1.98 ± 0.11 2.13 ± 0.08
Hippocampus 1.40 ± 0.23 1.20 ± 0.14

ΔFosB-ir was measured in homogenates prepared from brain regions of interest using an antibody against FosB that recognizes all FosB isoforms, as described in Methods. The 35–37 kDa band, defined as ΔFosB, was measured for analysis. Results are expressed as integrated intensity in units of counts-mm2 ± SEM.

*

p < 0.05

***

p < 0.001 different from vehicle by Student’s t-test, n=8 mice per group.