Table 1.

Femoral Artery Balloon Angioplasty Injury Models

	Single Injury	Double Injury	PValue
Quantitative analysis
Percentage luminal stenosis	5.5% (2.5–9.7)	11% (8.0–17)	0.002
Neointimal thickness, mm	0.18 (0.08–0.32)	0.13 (0.09–0.24)	0.9
Medial thickness, mm	0.35 (0.31–0.40)	0.51 (0.46–0.54)	<0.001
Intima/media ratio	0.08 (0.04–0.16)	0.10 (0.07–0.15)	0.5
Adventitial microvessels	25 (10–83)	11 (9–15)	0.2
Semiquantitative analysis
Injury	2 (0–3)	0 (0–1)	0.4
Inflammation	1 (1–1)	1 (1–1)	0.3
Medial fibrosis	1.5 (0–2)	0.5 (0–1.5)	0.4
Fibrin/thrombus	0	0	1
Hemorrhage	0	0	1
Pigs (femoral injury sites), n	2 (4)	2 (4)	…

All values are median (IQR). Pvalues are from mixed-effects linear models (see the online-only Data Supplement).